Bulletin · UTC

Merged timeline: 188 items (blog publish time and listing createdAt in UTC). Page 4 of 4. For registry-only weekly slices, use /new.

  1. Skillanndata

    ### Anndata - name: "anndata" - description: "Data structure for annotated matrices in single-cell analysis. Use when working with .h5ad files or integrating with the scverse ecosystem. This is the data format skill—for…

    by Yash @ ExplainxScience0 comments
  2. ### Uniprot Database - name: "uniprot-database" - description: "Access protein metadata, function, taxonomy, and sequences across UniProtKB, UniParc, and UniRef. Use when searching for proteins, mapping identifiers, or…

    by Yash @ ExplainxScience0 comments
  3. ### Quickgo Database - name: "quickgo-database" - description: "Query the QuickGO and Evidence & Conclusion Ontology (ECO) REST API. Use this when you need to map genes to biological processes, molecular functions, or c…

    by Yash @ ExplainxScience0 comments
  4. ### Unibind Database - name: "unibind-database" - description: "Queries the UniBind database for experimentally validated transcription factor (TF) binding sites. Use when retrieving direct TF-DNA interaction datasets,…

    by Yash @ ExplainxScience0 comments
  5. ### Gnomad Database - name: "gnomad-database" - description: "Query the Genome Aggregation Database (gnomAD). Use when determining the rarity or allele frequency of specific genetic variants, retrieving gene constraint…

    by Yash @ ExplainxScience0 comments
  6. ### Workflow Skill Creator - name: "workflow-skill-creator" - description: "Distills a completed user workflow or interaction into a reusable agent skill. Use when the user asks to turn their workflow, interaction, or m…

    by Yash @ ExplainxScience0 comments
  7. ### Literature Search Arxiv - name: "literature-search-arxiv" - description: "Search for scientific papers, preprints, and publications on arXiv. Extract metadata, abstracts, and download full-text PDFs or HTML versions…

    by Yash @ ExplainxScience0 comments
  8. Skillpymol

    ### Pymol - name: "pymol" - description: "Visualize, analyze, and render protein and molecular structures using PyMOL. Use when the user wants to create images of protein structures, perform structural alignments or sup…

    by Yash @ ExplainxScience0 comments
  9. Skilluv

    ### Uv - name: "uv" - description: "Checks whether the uv Python package manager is installed and installs it if missing. Ensures uv is on PATH. Use when another skill requires uv as a prerequisite."

    by Yash @ ExplainxScience0 comments
  10. ### Pubchem Database - name: "pubchem-database" - description: "Query PubChem, search by name/CID/SMILES, retrieve properties, similarity/substructure searches, bioactivity, for cheminformatics. Use when a user asks abo…

    by Yash @ ExplainxScience0 comments
  11. ### Clinical Trials Database - name: "clinical-trials-database" - description: "Query ClinicalTrials.gov via APIv2. Use when you want to search for trials by condition, drug, location, status, or phase; retrieve trial d…

    by Yash @ ExplainxScience0 comments
  12. ### Ucsc Conservation And Tfbs - name: "ucsc-conservation-and-tfbs" - description: "Fetch Evolutionary Conservation scores (phyloP, phastCons) and Transcription Factor Binding Sites (TFBS) from the UCSC Genome Browser.…

    by Yash @ ExplainxScience0 comments
  13. ### Human Protein Atlas Database - name: "human-protein-atlas-database" - description: "Use when you want to retrieve semi-quantitative protein expression and spatial localisation data from the Human Protein Atlas (HPA)…

    by Yash @ ExplainxScience0 comments
  14. ### String Database - name: "string-database" - description: "Query the STRING database for protein-protein interactions (PPIs), functional enrichment, and homology. Use when the user asks about interactions between spe…

    by Yash @ ExplainxScience0 comments
  15. ### Pubmed Database - name: "pubmed-database" - description: "Search PubMed for scientific literature, including published clinical trials. Fetch abstracts and full text. Link published research to biological databases…

    by Yash @ ExplainxScience0 comments
  16. ### Gtex Database - name: "gtex-database" - description: "Use when you want to retrieve quantitative RNA expression data and variant eQTL information from the GTEx (Genotype-Tissue Expression) Project across 54 non-dise…

    by Yash @ ExplainxScience0 comments
  17. ### Scienceskillscommon - name: "scienceskillscommon" - description: "Shared Python package for Science Skills, currently containing http_client -- a unified HTTP client with rate limiting, retries, and exponential back…

    by Yash @ ExplainxScience0 comments
  18. ### Ensembl Database - name: "ensembl-database" - description: "Query the Ensembl database to resolve gene, transcript, and protein IDs, fetch genomic or protein sequences, retrieve gene structures (exons), and get vari…

    by Yash @ ExplainxScience0 comments
  19. ### Protein Sequence Similarity Search - name: "protein-sequence-similarity-search" - description: "Searches for homologous protein sequences using MMseqs2 (fast, default) or BLAST (comprehensive, fallback). Trigger thi…

    by Yash @ ExplainxScience0 comments
  20. ### Literature Search Biorxiv - name: "literature-search-biorxiv" - description: "Browse, filter, and download life sciences, biology, and medical preprints from bioRxiv and medRxiv. Supports fetching paper metadata by…

    by Yash @ ExplainxScience0 comments
  21. ### Pdb Database - name: "pdb-database" - description: "Use when you want to search for or download experimentally-determined 3D structures for biomolecules (proteins, nucleic acids, bound ligands). Supports searching b…

    by Yash @ ExplainxScience0 comments
  22. ### Reactome Database - name: "reactome-database" - description: "Query the Reactome database (Analysis and Content Services). Use when the user asks about pathway analysis, gene list enrichment, retrieving results by t…

    by Yash @ ExplainxScience0 comments
  23. ### Embl Ebi Ols - name: "embl-ebi-ols" - description: "Query and search the EMBL-EBI Ontology Lookup Service (OLS) for biomedical ontology terms, definitions, and hierarchies across 250+ ontologies (e.g., GO, DOID, HP)…

    by Yash @ ExplainxScience0 comments
  24. ### Chembl Database - name: "chembl-database" - description: "Query the ChEMBL database for bioactive molecules, drug targets, bioactivity data, approved drugs, and chemical structures. Use when the user asks about comp…

    by Yash @ ExplainxScience0 comments
  25. ### Encode Ccres Database - name: "encode-ccres-database" - description: "Query the ENCODE Registry of cis-Regulatory Elements (cCREs) via the SCREEN GraphQL API, or make custom queries to the ENCODE Portal REST API for…

    by Yash @ ExplainxScience0 comments
  26. ### Interpro Database - name: "interpro-database" - description: "Identify domains, families, and sites in proteins; find all proteins in a family or sharing a domain; explore species distribution for a domain; annotate…

    by Yash @ ExplainxScience0 comments
  27. ### Protein Sequence Msa - name: "protein-sequence-msa" - description: "Performs multiple sequence alignment of proteins with EBI Clustal Omega. Use when you need to align multiple sequences to assess similarity, domain…

    by Yash @ ExplainxScience0 comments
  28. ### Foldseek Structural Search - name: "foldseek-structural-search" - description: "Performs 3D structural searches of proteins against various databases (PDB, AlphaFold, CATH, MGnify, etc.) using the Foldseek API. Use…

    by Yash @ ExplainxScience0 comments
  29. ### Opentargets Database - name: "opentargets-database" - description: "Query Open Targets Platform for target-disease associations, drug target discovery, tractability/safety data, genetics/omics evidence, known drugs,…

    by Yash @ ExplainxScience0 comments
  30. ### Openfda Database - name: "openfda-database" - description: "Query, search, and download data from the openFDA API for drugs, devices, foods, tobacco, cosmetics, animal and veterinary products, substances, and transp…

    by Yash @ ExplainxScience0 comments
  31. ### Ncbi Sequence Fetch - name: "ncbi-sequence-fetch" - description: "Retrieve protein and nucleotide sequences from NCBI databases using E-utilities. Supports direct accession lookup, CDS translation, gene+organism sea…

    by Yash @ ExplainxScience0 comments
  32. ### Alphagenome Single Variant Analysis - name: "alphagenome-single-variant-analysis" - description: "Analyzes genetic variant effects on gene expression (RNA-seq), chromatin accessibility (DNASE), histone marks (ChIP),…

    by Yash @ ExplainxScience0 comments
  33. Miso 1 is the most emotive voice model in the world, capable of human-like emotional responses and fast reaction times. It is open source and comes with a full API for developers to build upon.

    by Yash @ ExplainxMisa Labs0 comments
  34. Gemma 4 is an advanced model built from Gemini 3 research, designed to maximize intelligence-per-parameter. It supports multimodal reasoning and is optimized for various applications, including mobile and IoT devices.

    by Yash @ ExplainxGoogle DeepMind0 comments
  35. Google DeepMind's Gemma 4 12B is a breakthrough open-source model that delivers flagship-level multimodal capabilities on consumer hardware. Here's everything you need to know about architecture, benchmarks, deployment, and use cases.

  36. Microsoft Research's SkillOpt revolutionizes agent development by treating skill documentation as trainable state rather than static prompts. Early adopters report +20 point accuracy improvements and cross-platform skill transfer.

  37. Miso Labs' Miso-TTS is the fastest and most emotive open-source voice foundation model. With 110ms latency, one-shot cloning, and local deployment, it's built for production voice agents that users actually love.

  38. NVIDIA's Cosmos 3 release turns Cosmos from a broad world-model platform into an open developer stack for omnimodal Physical AI. This guide explains the Reasoner and Generator surfaces, the model family, supported inputs and outputs, setup paths, benchmarks, and where the limits still are.